Human Milk Oligosaccharides: Impact On Infant Gut Microbiome And Health

Breastmilk has been shown to support the child’s immunity. Though the exact mechanisms are still to be fully understood, these are attributed to the bioactive components, like immunoglobulins, hormones and growth factors, cytokines and anti-microbial compounds, found in the milk. In addition to this, it has been found that human milk oligosaccharides (HMOs), the third most abundant solid component of the milk, have direct effects in protecting the infant from pathogens.

Prof. Martin Laursen discusses the new evidence that correlates HMOs to the establishment of a healthy gut microbiota in early life, which in turn produce immune-regulatory metabolites and build up the child’s defense system. He also discusses how this may be applied to infant nutrition, especially when breastfeeding is not possible for the mother and baby.