Do HMOs have a role in reducing the risk of NEC?

1 min read /
Nutrition & Disease Management
Do HMOs have a role in reducing the risk of NEC? (infographics)
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HMOs may play a role in reducing the risk of necrotising enterocolitis (NEC), one of the most common and life-threatening gastrointestinal disorders in preterm infants.

  • Infants who are fed exclusively with human milk instead of infant formula are 6 to 10 times less likely to develop NEC
  • Lower diversity of HMOs may be associated with the development of NEC in very-low-birth-weight-infants
  • Low levels of disialyllacto-N-tetraose (DSLNT) in mother’s milk may be related with an increased risk of NEC in preterm infants
  • Preclinical studies suggest that infant formulae, when supplemented with pooled HMOs, improved the NEC survival rate and reduced the symptoms of NEC
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